Welcome to the Cheema Lab
We are a small, dynamic group at the Georgetown Lombardi Comprehensive Cancer Center. Our aim is to explore and understand metabolomics data in a variety of areas including radiation biology, cancer and neurodegenerative disease.
As way of background, metabolomics provides a qualitative and quantitative description of small (<1 kD) molecules (metabolites) involved in metabolism and their connected pathways. It encompasses a wide variety of metabolites, including those found naturally in the body, such as glucose or cholesterol, as well those from external sources like diet and environment. Overall, metabolomics offers a snapshot of complex biological systems required for health and perturbed in disease.
At Cheema Lab, the power of metabolomics has already been demonstrated in a variety of disease states including cancer, Alzheimer’s, infectiousdisease, alcoholic liver disease, inflammatory conditions including inflammatory bowel diseases, radiation injury, diabetes, transplantation medicine, and many others. Given the multidisciplinary nature of a systems biology approach, metabolomics has direct applicability to numerous fields including molecular biology, cancerbiology, neuroscience, toxicology, nutrition, radiobiology, chemistry, physics, environmental science, mathematics/mathematical-modeling, translational sciences, botany, food and agricultural studies, drug development, personalized medicine, and the microbiome.
News
Sept 23, 2019
Mackenzie Pearson, PhD, a Field Application Specialist from SCIEX hosted a Cardiolipin method training on our 5500 QTRAP.
Sept 4, 2019
Congratulations to our PhD Candidate Chaz Hinzman on receiving an NIH TL-1 pre-doctoral fellowship in the Georgetown-Howard Universities Center for Clinical and Translational Science program in Translational Biomedical Science! Funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), the goal of the Translational Biomedical Science (TBS) program offered through the Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is to prepare pre-doctoral students and post-doctoral fellows (MDs and PhDs) to serve as the critical link in advancing the translation of basic science into improved outcomes for health, aging and disease.
July 22, 2019
Congratulations to our PhD Candidate Chaz Hinzman on receiving a 2019 Chinese Society of Clinical Oncology (CSCO) Young Investigator Travel Award. Thanks to CSCO and the American Association for Cancer Research (AACR), this award allows Chaz to attend the CSCO 2019 Annual Meeting in Xiamen, China to present his recent work that was shown as a poster presentation at the 2019 AACR meeting!
July 8, 2019
Albert J. Fornace Jr., MD, and Amrita Cheema, PhD, have founded the new Center for Metabolomic Studies (CMS), which will leverage the combined capabilities of Georgetown's Medical Center and Main Campus to study the emerging field of metabolomics and facilitate studies at both the basic and clinical-translational levels.Learn more
July 1, 2019
New publication - "Plasma-derived extracellular vesicles yield predictive markers of cranial irradiation exposure in mice. Sci Rep. "
May 6, 2019
Darren Dumlao, PhD, a Field Application Specialist from SCIEX hosted a Fluxomics and Metabolomics training on our 5500 QTRAP.
March 24, 2019
Otis Bervely, PhD, a Technical Specialist from Waters hosted an in-depth MRM-MS training on our TQ-S.
Feb 4, 2019
Mackenzie Pearson, PhD, a Field Application Specialist from SCIEX hosted a Lipidyzer training on our 5500 QTRAP platform.
January 26, 2019
Instrument installation training for our SCIEX 5500 QTRAP.